IL6 and acute kidney injury: In a randomized crossover double-blind study enrolling 16 sepsis-associated AKI patients who had an endotoxin level higher than 0.03 EU/mL, Broman et al. found that CRRT with the oXiris hemofilter was associated with a greater removal of endotoxins and cytokines (namely, TNF-α, IL-6, IL-8, and IFN-γ) than that with a standard AN69ST hemofilter (Baxter, Meyzieu, France) [13].