A study of patients with acute myocardial infarction (AMI) found that plasma angiopoietin 2 (Ang-2) levels (6338.28 ± 5862.77 versus 2412.03 ± 1256.58 pg/mL) and thrombomodulin (TM) levels (7.6 ± 2.26 versus 5.34 ± 2.0 ng/mL) were higher in patients with AKI than in those without AKI [88]. The gene discussed is ANGPT2; the disease is acute kidney injury.