Brun-Olszewska et al. reported, when comparing CDF patients with neuropathy patients and, respectively, patients with DM, no genotype changes for three out of ten analyzed loci: OPG 950T/C, RANK 421C/T, and RANK 575C/T, while genotype changes were present for C genotype in the case of OPG 1181C/G, for CC genotype in OPG 6890A/C, for the identical genotype in OPG 245T/G and OPG 1217 C/T in patients with CDF [20]. This evidence concerns the gene TNFRSF11B and neuropathy.