ACP5 and diabetes mellitus: Petrova et al., comparing patients with CDF to patients with DM and without DM, reported an increased value for C-terminal telopeptide (0.24 versus 0.12 versus 0.15 μg/L, p = 0.004) alongside bone alkaline phosphatase (b-ALP) (16.4 versus 13.6 versus 10.1 μg/L, p = 0.006) and no statistically significant decrease in tartrate-resistant acid phosphatase (3.9 versus 2.7 UI/L, p = 0.126) [16] (Table 2).