At the time of analysis, KLF-14-rs972283 G>A, eNOS3-rs1799983 G>T and miRNAs27ars895819 A>G SNP were studied in 125 CAD cases and 125 controls, and MTHFR 677 C>T gene polymorphism was analyzed in 116 CAD cases and 125 healthy controls. This evidence concerns the gene MTHFR and coronary artery disorder.