DISC1 and psychiatric disorder: The study of the protein’s structure demonstrated the internal irregularity of the N-terminal region of DISC-1 and identified four functional helical and soluble domains in the C-terminal region, named D. I. S. C. The C-terminal region may determine the pathophysiology of mental illness associated with protein assembly and aggregation disorders, since previously discovered mutations for the most part affected this part of the protein [96].