The activation of CYP1A effectively controls the pro-oxidants and oxidative stress in colon cancer cells further, suppressing the proinflammatory cytokines IL-1β and TNF-α, which favors the deactivation of malignant cell apoptosis inhibitor NF-kB in colon cancer cells [26]. This evidence concerns the gene NFKB1 and malignant colon neoplasm.