LGALS4 and Alzheimer disease: In the control group, the F1 generation obtained by crossing of GS-Gal4>Aβ42 flies and w1118 flies were fed sucrose–yeast (SY) food with 200 μM RU486 to induce ubiquitous Aβ42 expression (i.e., GS-Gal4>Aβ42 >+ +RU flies, this is the Drosophila AD model).