NLRP3 and COVID-19: Quercetin, as an anti-inflammatory compound, may be an effective treatment for severe inflammation, one of the main life-threatening conditions in patients with COVID-19, by suppressing the production of pro-IL-1β and the NLR family pyrin domain containing 3 (NLRP3) inflammasome by affecting its regulators, such as TXNIP, SIRT1, and Nrf2 [78].