Moreover, we did not detect any deviation from the HWE for either ADORA2A rs5760423 (p = 0.82 and p = 0.74, for the AD and the healthy control groups, respectively) or CYP1A2 rs762551 (p = 0.71 and p = 0.63, for the AD and the healthy control groups, respectively). This evidence concerns the gene CYP1A2 and Alzheimer disease.