HILPDA and nonpapillary renal cell carcinoma: Recently, it has been shown that two LD-associated proteins, lipid droplet protein perilipin 2 (PLIN2) and hypoxia-inducible lipid droplet-associated (HILPDA), are overexpressed in ccRCC, where they regulate lipid storage and enrich lipids that contain polyunsaturated fatty-acyl side chains [128,129].