Challenging OBCs-SN with TNF-α induced a concentration-dependent decrease in the TH+ DOPAn number, with 60 ng/mL TNF-α replicating the dopaminergic loss observed in the PD model (Figure 5A, TNF-α: pink bars, 40%, p < 0.05 vs. Ctrl: blue bar, compare with grey bar: Rot). The gene discussed is TNF; the disease is Parkinson disease.