SOD1 and Cirrhosis: In studies conducted on a group of 60 clinically healthy volunteers and 30 patients with cirrhosis of the liver aged 25–45 years, the highest activity of SOD-1 was shown at 6 a.m., while the lowest activity was at 6 p.m. In both cases, the peaks coincided, but the enzyme values were lower in patients with cirrhosis compared to the healthy group of volunteers.