TGFB1 and Hyperglycemia: We found that the blood levels of active TGFβ1 were significantly increased in the diabetic TGFβ1 TG (TGFβ1 TG/STZ) compared to the non-diabetic TGFβ1 TG (TGFβ1 TG/SAL) mice and diabetic WT mice (WT/STZ), suggesting an enhanced TGFβ1 activation in the presence of hyperglycemia.