Here, we describe a heterozygous non-synonymous variant (p.Arg930His) in the CACNA1D gene identified in a three-generation Turkish family with a phenotype composed of cardiac and neurologic symptoms including sinus bradycardia, atrio-ventricular block (AVB), idiopathic epilepsy and learning disability, but without signs for congenital deafness. Here, CACNA1D is linked to Sinus bradycardia.