Correspondingly, BMAL1 knockdown increased the expressions of epithelial markers (E-cadherin, CK-20, and EpCAM) but decreased the expressions of TWIST and mesenchymal markers (N-cadherin and vimentin) in CRC cell lines (HCT116 and SW480), promoting mesenchymal-epithelial transition (MET)-like changes in these cells [126]. Here, BMAL1 is linked to colorectal carcinoma.