The RANBP2 gene mutations have been associated with the ANE in children [53,54], some other genes regarding metabolism or immunity, including neuronal sodium channel alpha 1 (SCNIA) and carnitine palmitoyltransferase II (CPT2), human thiamine transporter 2 (hTHTR2) have been also linked with the ANE after an infection [55,57,58]. The gene discussed is RANBP2; the disease is infection.