PPARA and obesity due to melanocortin 4 receptor deficiency: Lactobacillus kefiri DH5 (Lentilactobacillus kefiri in new nomenclature, [64]) [66], Lactobacillus amylovorus CP1563 [67,68] and Lactobacillus plantarum (Lactiplantibacillus plantarum) FRT10 strains [69] induced Ppara expression and PPARα function in liver and adipocytes, which ameliorated the liver steatosis parameters in NAFLD or obesity in HFD mice [69].