The harmful potential of alcohol consumption summed to other health risk factors, such as Helicobacter pylori infection, smoking, poor oral hygiene, an unhealthy diet, ALDH2 deficiency, dietary intake of acetaldehydes, exposure to certain chemicals related to labor occupation and viral infections, among others, can exacerbate cancer risk [74,75]. The gene discussed is ALDH2; the disease is hyperinsulinemic hypoglycemia, familial, 4.