Additionally, mutations of the Cell Division Cycle 73 (CDC73) [100] tumor-suppressor gene (previously known as HRPT2) are associated with the Hyperparathyroidism-Jaw Tumor (HPT-JT) syndrome, an autosomal dominant disease whose clinical manifestations are mainly parathyroid tumors and, less frequently, ossifying fibromas of the jaw, as well as uterine and renal tumors. The gene discussed is CDC73; the disease is autosomal dominant disease.