RHO and cancer: As shown in Figure 3, the up-regulated genes group showed that the ten most overrepresented biological processes were: cellular response to hormone stimulus (GO:0032870), protein phosphorylation (GO:0006468), regulation of cellular response to stress (GO:0080135), intracellular protein transport (GO:0006886), regulation of cellular localization (GO:0060341), pathways in cancer (HSA05200), neuron projection development (GO:0031175), RHO GTPase cycle (R-HAS-9012999), regulation of growth (GO:0040008), and signal transduction by p53 class mediator (GO:0072331).