SKAP2 and infection: Similar to our observations made with the macrophage survival assays, we observed similar killing rates when larvae were infected with the WT and the trans-complemented ΔsapS derivative harboring plasmid pLI50_SapS_D103A (Figure 11C), indicating that SapS phosphatase activity is also not important for infectivity of S. aureus in this in vivo model of infection.