It has been shown that ccRCC is characterized by a significant accumulation of polyunsaturated fatty acids (PUFAs), in association with overexpression of stearoyl-CoA desaturase-1 (Δ-9-desaturase; SCD1) and fatty acid elongase 2 and 5 (ELOVL2 and ELOVL5) [16]. This evidence concerns the gene ELOVL5 and nonpapillary renal cell carcinoma.