Livers from mice and patients with pancreatic ductal carcinomas bared DTCs that lacked expression of the major histocompatibility complex I (MHC I) and cytokeratin 19 (CK19) tumor antigen, providing evidence for a novel immune escape pathway which involves the evasion of T cell killing upon recognition under endoplasmic reticulum (ER) stress [85]. The gene discussed is KRT19; the disease is neoplasm.