KEGG analysis showed that the co-targets of GCK and osteoporosis were mainly involved in 88 pathways (the top 20 pathways are shown in Figure 7), most of which were cancer-related pathways (such as pathways in cancer, proteoglycans in cancer, prostate cancer, pancreatic cancer, non-small cell lung cancer and so on). This evidence concerns the gene GCK and osteoporosis.