TNF and infection: However, a meta-analysis revealed that the pooled ORs for serious infections in abatacept users were non-significant when compared with csDMARD users (OR = 1.35, 95% CI 0.78–2.32) [128], and the risk for hospitalized infection was lower than TNF inhibitor users in patients with RA (HR = 0.78, 95% CI 0.64–0.95) [129].