The correlations between the gut microbiota genera and serum metabolite biomarkers are shown in Figure 7A, where metabolites were more highly correlated with serum endotoxemia (endotoxin and LBP), body proinflammatory response cytokines (IL-6 and TNF-α), adipocytokines (adiponectin and leptin), and hepatic proinflammatory cytokines (IL-6, TNF-α, IL-1β). The gene discussed is LEP; the disease is serum lipopolysaccharide activity.