In addition, IFNy (p = 0.007), IL-10 (p = 0.02), IL-17A (p = 0.007), and IL-2 (p = 0.02) levels were higher, while IL-8 levels were lower (p = 0.03) in patients with a disease duration of fewer than 7 years compared with individuals suffering from SLE for more than 7 years. This evidence concerns the gene IL10 and systemic lupus erythematosus.