IL10 and systemic lupus erythematosus: Patients with SLE show a significant increase in classical pro- and anti-inflammatory cytokines involved in the pathogenesis of SLE, including TNF-α (p = 1.3 × 10−4), IL-1b (p = 0.005), IL-6 (p = 8.2 × 10−5), and IL-10 (p = 0.005).