MUC16 and uterine corpus leiomyoma: Moreover, female patients who smoke or develop inflammatory processes, as well as those with physiological or benign conditions (e.g., menstruation, pregnancy, uterine fibroids), might display altered serum CA125 levels, thereby increasing false positive rates and HGSOC misdiagnoses [33,34,35,36,37,38,39,40,41,42,43,44].