HSF2 and Familial prostate cancer: To date, only Fan and his colleagues reported that HSF2 is positively involved in esophageal squamous cell carcinogenesis; however, aberrant regulation of miR-202 was also reported in human osteosarcoma, colorectal carcinoma, lung cancer, pancreatic cancer, bladder cancer, and prostate cancer [128,129,130,131,132,133].