HSF2 and colorectal adenocarcinoma: They also changed the expression of HSF2 in Caco-2 colorectal adenocarcinoma cells by lentiviral transfection, and found that the expression of Bax, cytoplasmic Cyto-C, Cleaved Caspase-9, and Cleaved Caspase-3 were negatively correlated with the different levels of HSF2.