As it happens, the publication of many papers demonstrating that HSF2 is involved in carcinoma and tumor formation has increased since the year 2016, almost all of them indicating that HSF2 is positively involved in cancer cell growth, survival, proliferation, and tumor formation; however, no other papers referring to the relationship between HSF2 and prostate cancer have been published since the report of Nees and Sistonen group. Here, HSF2 is linked to Familial prostate cancer.