Other retinal degenerative models, transgenic RHO P347S and Prp2rds+/− (perpherin-2, retinal degeneration slow) mice, manifest similar p-STAT3 (Y705) levels in Müller glia, in addition to a weak immunoreactivity for p-STAT3 in photoreceptors [26]. Here, STAT3 is linked to retinal degeneration.