TNF and rheumatoid arthritis: In one study, it was identified that patients with rheumatoid arthritis receiving intravenous infliximab had lower bleeding on probing scores, lower concentrations of tumor necrosis factor-alpha in gingival crevicular fluid, and lower mean probing depth measurements than patients with rheumatoid arthritis who were not receiving antitumor necrosis factor alpha therapy and with non-rheumatoid arthritis controls [99].