ERBB2 and breast cancer: Table 3 displayed the top 10 targets according to the normalized fit score of protein No. 1. We chose the protein that came in eighth place among them, and it is a human-derived protein linked to cancer. The protein (PDB code: 1N8Z [23]) is the extracellular domain of human HER2 complexed with Herceptin Fab. This complex had been linked to breast cancer [23]. Interestingly, as indicated in Table 4, this protein was also present in the top 10 targets of protein No. 7. So, for each of them, we used the extracellular domain of human HER2 complexed with Herceptin Fab [23] as the target protein.