Moreover, Anaerotruncus and Lachnoclostridium, which are described as mucin-degrading bacteria that can impact both glycan composition and mucus thickness participating in the degradation of mucin [59], were increased in NAFLD mice in this study, which correlated with other preclinical studies [60,61], supporting the association of impaired intestinal barrier function with NAFLD. The gene discussed is MUC5AC; the disease is metabolic dysfunction-associated steatotic liver disease.