On the other hand, antioxidant defenses and innate immune system defenses against inflammation and bacterial infections are decreased in deficit schizophrenia, including sulfhydryl groups, total radical antioxidant trapping parameter (of plasma), paraoxonase 1 (PON1) activity, IgM responses to a variety of oxidative specific epitopes and TRYCATs [65]. Here, CD40LG is linked to schizophrenia.