IL6 and schizophrenia: These schizophrenia phenotypes are characterized by increased neuroimmunotoxic biomarkers, including interleukin (IL)-1, IL-6, IL-17, tumor necrosis factor (TNF)-α, and eotaxin (CCL-11) [20,21], and activation of the tryptophan catabolite (TRYCAT) pathway with increased levels of IgA directed to neurotoxic TRYCATs such as picolinic (PA), xanthurenic (XA) and quinolinic acid (QA) and 3-OH-kynurenine (3OHK) [20,21].