On the other hand, antioxidant defenses and innate immune system defenses against inflammation and bacterial infections are decreased in deficit schizophrenia, including sulfhydryl groups, total radical antioxidant trapping parameter (of plasma), paraoxonase 1 (PON1) activity, IgM responses to a variety of oxidative specific epitopes and TRYCATs [65]. Here, PON1 is linked to bacterial infectious disease.