EGFR and neoplasm: However, a comparison of tumor grade revealed that compared with the EGFR-mutant patients, the EGFR wild-type patients had a higher prevalence of poor cell differentiation (20.7% vs. 6.0%, p = 0.001) and lower rates of well-differentiated cells (7.2% vs. 11.4%, respectively, p = 0.001) and moderately differentiated cells (72.1% vs. 82.5%, p = 0.001) (Table 1).