In addition, polyphenols and flavonoids have been proven to prevent obesity by inducing the browning of white adipose tissue (WAT) and regulating the expression of factors such as C/EBPα, SREBP-1C, ACC, and FASN, which relate to the synthesis of fatty acids [36]. The gene discussed is CEBPA; the disease is obesity due to melanocortin 4 receptor deficiency.