Finally, a single injection of cyclophosphamide, a drug able to induce ICD, can increase the Cxcl9, Cxcl10 and Cxcl11 expression within mastocytoma tumors (an effect dependent on CD4 T cells), thus allowing the recruitment of CD8 T cells and tumor regression [71]. The gene discussed is CXCL11; the disease is neoplasm.