C1GALT1 is highly expressed in head and neck squamous cell carcinoma (HNSCC), breast cancer (BC), esophageal carcinoma (ESCA), hepatocellular carcinoma (HCC), and laryngocarcinoma, enhancing the malignant phenotype of cancer cells and it is associated with a poor survival rate and poor prognosis of patients [42,43,44]. This evidence concerns the gene C1GALT1 and breast carcinoma.