MUC1 and breast cancer: Lakshminarayanan et al. designed a glycosylated vaccine for a mouse breast cancer model consisting of a TLR1/2 ligand (Pam3CysSK4), a T-helper cell (Th) epitope, and an abnormal MUC1 peptide that produces cytotoxic T cells (CTL) that recognize both glycosylated and nonglycosylated peptides, whereas a similar nonglycosylated vaccine-generated CTL can only recognize nonglycosylated peptides.