B4GALNT3 and cancer: The N-acetylgalactosaminyltransferases β4GalNAcT3 and β4GalNAcT4 can transfer GalNAc to GlcNAc residue in both N- and O-glycans to generate LacdiNAc antigen, which is also a valid biomarker for different cancers or even different stages of certain cancers [12].