Due to their similar structures and synthetic pathways, STn antigen and Tn antigen are often upregulated simultaneously in tumor cells at the same time, and STn antigen expression upregulated has been shown to contribute to tumorigenesis, and is associated with a poor prognosis in cancer patients, including gastric, colon, breast, lung, esophageal, prostate, and endometrial cancers [60]. This evidence concerns the gene EEF1A2 and cancer.