Our protein library contained 17 proteins in the context of an infection (CMV, HPV, EBV, HBV, mumps, LPS), tumor and cellular stress response (HSP27, HMGB1, CRT, HO-1, HO-2, IL8), autoimmunity (insulin, collagen, vimentin, albumin) or others (ovalbumin, bovine serum albumin). This evidence concerns the gene HMGB1 and infection.