Ding et al. [73] revealed that lncRNA MALAT1 regulates the NF-κB signaling pathway in LPS-induced AKI via the modulation of miR-146a expression, providing new insights into the complex molecular mechanisms of specific miRNAs and lncRNAs in LPS-induced AKI (Figure 4). This evidence concerns the gene NFKB1 and acute kidney injury.