Another study suggested that EMPA significantly improves NAFLD-related liver injury by enhancing the autophagy of hepatic macrophages through the AMPK/mammalian target of the rapamycin (mTOR) signaling pathway and further inhibiting the interleukin (IL)-17/IL-23 axis-mediated inflammatory response [126]. The gene discussed is MTOR; the disease is metabolic dysfunction-associated steatotic liver disease.