The plot shows that very low content of OC positive Aβs oligomers was found in samples N1-B11, N2-B11 and N3-B11 from normal brains, whereas high content of OC positive oligomers was detected in all the samples from AD affected brains AD1-B11, AD2-B11 with particular high immunoreactivity in AD3-B11/TEC samples. This evidence concerns the gene DDX41 and Alzheimer disease.