Many hematologic and solid tumors overexpress CD47, including acute and chronic myeloid leukemia (AML and CML) [9], acute lymphoblastic anemia [10], non-Hodgkin’s lymphoma (NHL) [11], multiple myeloma (MM) [12], and in solid cancers such as bladder, prostate, ovarian, lung, kidney, stomach cancers, hepatocellular carcinoma, gliomas, glioblastoma multiforme [13]. Here, CD47 is linked to acute myeloid leukemia.