For example, the members of the miR-200 family, miR-141 and miR-200a, target C-X-C motif chemokine ligand 12 (CXCL12; also known as CXCL12β) to regulate the immunosuppressive activity of a subtype of carcinoma-associated fibroblasts in ovarian cancer [154]. This evidence concerns the gene CXCL12 and ovarian cancer.