Furthermore, a group of studies has consistently demonstrated that stimulating the low-affinity receptor DRD1 in myeloid cells attenuates the activation of the inflammasome NLRP3, thereby dampening inflammation in several contexts, including neuroinflammation, lipopolysaccharide-induced systemic inflammation, and acute kidney injury [38,39,40,41]. This evidence concerns the gene NLRP3 and acute kidney injury.