The detailed CpGs in Figure 7 show that the following genese displayed higher expression levels in breast cancer: cg07263562 of CCNA2; cg13849825, cg13647309, cg17668562 of CCNB1; cg10792831, cg16397722 of TP53; cg07054526, cg16029534 of BRCA1; cg22935319 of TOP2A; cg11234767, cg15974867 of CCND1; cg02072813, cg06934468, cg10100767, cg01694276, cg20923444 of AKT1; cg16560077, cg01963870, cg27390443, cg27318635, cg03140190, cg05898629 of CREBBP; cg00400189 of SMAD4; cg12209876, cg03732055, cg09414638 of ESR1; cg21346648, cg24651824, cg27443373 of CENPE. The gene discussed is ESR1; the disease is breast carcinoma.