OAS2 and systemic lupus erythematosus: The gene expression analysis of PTPN22, OAS2, CD70, and IL10 according to the clinical features of SLE patients showed that patients with renal clinical manifestations had significantly decreased mRNA levels of PTPN22 and IL10 compared with patients without renal involvement (p = 0.007 and p = 0.033, respectively; Figure 2A).