Of the 22 genes identified in the chromosomal gain regions, those that maintained high expressions in leukemia-derived cell lines and in ALL patients (Figure 5 and Figure 6A,B) were NT5C3B, CNP, ACLY, JUP, KLHL11, RTL10, and GNB1L. The gene discussed is KLHL11; the disease is acute lymphoblastic leukemia.