CD40 and COVID-19: Conforming with previous reports [3], the level of the following markers, CA12, soluble CD40, IL-6, IL-8, soluble PD-L1, and VEGF, were significantly increased by 1.5-fold, 1.5-fold, 6-fold, 2-fold, 2-fold, and 1.5 fold, respectively, in COVID-19 deceased patients compared to control cohort (p ≤ 0.05) (Figure 2).