Cutaneous tumors such as angiofibroma, collagenoma, and lipoma are common findings and they particularly raise a MEN1 suspicion, needing to be differentiated from sporadic presentations, especially in patients with special features, as suggested by Asgharian et al. (more than three angiofibromas or any collagenoma) [53]. This evidence concerns the gene MEN1 and Angiofibroma.