IGF1 and multiple endocrine neoplasia type 1: Of course, the level of statistical relevance varies from cohorts to case reports, but we decided not to restrain the research, knowing that MEN1 syndrome may associate unusual pathological entities which should be assessed in order to find out if they are accidental on an individual confirmed with MEN1, are caused by genetic background of the syndrome, or are due to some hormonal anomalies induced by the associated endocrine tumors and/or NETs, as seen by IGF-1 excess [101,106].