MEN1 patients present lactotroph tumors (the most frequent pituitary NETs associated with MEN1, followed by somatotroph tumors) in addition to primary hyperparathyroidism (which typically appears around the age of 20–25 years and is more frequently accompanied by nephrolithiasis than non-MEN hyperparathyroidism) [24,25,26,27,28,29,30]. This evidence concerns the gene MEN1 and growth hormone-producing pituitary gland neoplasm.